Towards the total synthesis of keramaphidin B
نویسندگان
چکیده
The enantio- and diastereoselective Michael addition of a δ-valerolactone-derived pronucleophile to a substituted furanyl nitroolefin catalysed by a bifunctional cinchonine-derived thiourea has been used as the key stereocontrolling step in a new synthetic strategy to the heavily functionalised piperidine core of keramaphidin B.
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عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2016